Endometrial Cancer Staging

Manual
AI (beta)

Histology Type

Endometrioid
Serous
Clear cell
Carcinosarcoma
Undifferentiated
Mucinous
•••

Grade

Grade 1
Grade 2
Grade 3
High grade by definition

Tumor Involvement

Endometrium, Myometrium, Serosa

Endometrium
Endometrial polyp
Myometrium
 ••• 
Uterine subserosa or serosa

Cervix, Parametrium, Vagina

Cervical stroma
Cervical gland
Parametrium
Vagina

Ovary, Fallopian Tube

Ovary
 ••• 
Fallopian tube

Peritoneum, Bladder, Intestine, Distant Metastasis

Peritoneum within pelvis (e.g. Cul-De-Sac, rectum serosa...)
Peritoneum beyond pelvis (e.g. Omentum, liver surface...)
Bladder mucosa
Intestinal mucosa
Liver
Lung
Brain
Bone

Lymphovascular Space Invasion (LVSI)

Absent
Focal
Substantial

Lymph Node (LN) Status

1. Pelvic lymph node
Negative
≤0.2mm
*ITCs
>0.2-2mm
Micro-meta
>2mm
Macro-meta
2. Para-aortic lymph node
Negative
≤0.2mm
*ITCs
>0.2-2mm
Micro-meta
>2mm
Macro-meta
3. Extra- or Intra-abdominal LN above the renal vessels
Negative
Positive
*ITCs: isolated tumor cells.

Molecular Classification

1. POLE mutation status
Negative
Positive
(POLE mutation)
Not tested
2. MMR deficiency status (MSH6, PMS2)
Negative
Positive
(MMR deficiency)
Not tested
3. p53 abnormal status
Negative
Positive
(p53 abnormal)
Not tested
4. No Specific Molecular Profile (NSMP): Not applicable (incomplete POLE/MMR/p53 data).

AJCC 8th

 

FIGO 2023

  

FIGO 2009

 
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ESMO Risk Group

Low
Risk
Intermediate
Risk
High-int.
Risk
High
Risk
Please select the corresponding pathologic status.
Ann Oncol. 2022 Sep;33(9):860-877

Management Suggestion

Under Construction